Guard Column cartridges, Bidentate C8 2.o, replacement, 2.0 mm ID x 10 mm long cartridges packed with 2.2 um, 120 A phase. Cogent TYPE-C Brand. 5/PK.
Additional Info:
The 40208‑PG2 Cogent Bidentate C8 2.0 Guard Column Cartridges are replacement cartridges engineered for UHPLC and high‑pressure analytical systems, where maintaining column performance and preventing system contamination is critical.
Each cartridge is:
2.0 mm ID × 10 mm length
Packed with 2.2 µm, 120 Å TYPE‑C™ silica hydride Bidentate C8 2.0 phase
Constructed in stainless steel hardware with SS frits
Cartridges are individually packaged in protective Delrin™ cases, preventing drying, contamination, or physical damage before installation.
⚠️ Requires guard column holder (sold separately)
Designed for 2.1 mm UHPLC Columns
These cartridges are optimized for:
2.1 mm ID analytical and UHPLC columns
Sub‑2 µm particle methods
LC‑MS workflows requiring high sensitivity
Proper guard matching ensures:
Minimal band broadening despite small particle size
Maintained efficiency and resolution
Stable retention and reproducibility
Why Use UHPLC Guard Cartridges
UHPLC columns (2.2 µm particles) are highly sensitive to:
Particulates and debris
Strongly retained contaminants
Sample matrix buildup
Pressure increases from blockage
The 40208‑PG2 cartridges act as a critical protection layer, helping to:
Preserve UHPLC column efficiency
Prevent pressure spikes and system clogging
Extend analytical column lifetime
Maintain consistent high‑resolution results
Cartridges can be replaced quickly without disturbing the analytical column setup.
Bidentate C8 2.0™ Guard Phase Advantages
Using a matched phase ensures:
No change in retention or selectivity
Seamless analyte transfer
No need for method re‑validation
Compared to C18:
Reduces excessive hydrophobic retention
Improves recovery of amine‑containing compounds
Provides alternative selectivity in complex separations
Enables faster equilibration in gradient methods
Cogent TYPE‑C™ Technology Benefits
Silica Hydride Surface
Reduced silanol activity
Improved peak shape for basic analytes
Lower secondary interactions
High‑Pressure Stability
Designed for UHPLC / sub‑2 µm workflows
Compatible with elevated system pressures
Maintains performance under demanding conditions
Faster Equilibration
Reduced cycle times
Increased throughput for high‑efficiency methods
Typical Applications
UHPLC and LC‑MS analytical methods
Pharmaceutical and bioanalytical workflows
High‑resolution separations
Complex sample matrices
Methods using sub‑2 µm Bidentate C8 columns